Decentralized autonomous organization (DAO) HydraDAO claims to have achieved a breakthrough in spinal cord repair for paralyzed rats using a novel technique. In a recent post on May 5, decentralized science (DeSci) project HydraDAO shared that their research led to rats with fully transected spines being able to walk again within just five days post-surgery. The project, known as the Dowell spinal fusogens project, raised 380,700 USDC from donors to support the research. The team behind the project introduced a compound called neuro-PEG, which combines polyethylene glycol (PEG) with chitosan, a biopolymer from crustacean shells. This compound, which is photopolymerizable, has shown promising results in promoting membrane fusion and sealing axonal membranes, potentially aiding in the reconnection of severed nerve fibers. A research paper published in the peer-reviewed scientific journal Surgical Neurology International by project leader Michael Lebenstein-Gumovski reported that pigs treated with the compound regained mobility within two months of treatment. The team has also filed a patent for their developed technologies, aiming to commercialize specialized surgical kits and provide training for medical professionals. While the results are encouraging, further independent validation and research are required to determine the clinical viability of this technique for spinal cord injuries. The team’s approach has drawn comparisons to previous controversial claims in the field of neurosurgery, emphasizing the need for cautious optimism until additional data and studies are conducted.